Salicylates Increase Insulin Secretion in Healthy Obese Subjects
نویسندگان
چکیده
منابع مشابه
Insulin secretion and insulin sensitivity in relation to fasting glucose in healthy subjects.
OBJECTIVE This study evaluated insulin secretion and insulin sensitivity in healthy subjects with normal fasting glucose. RESEARCH DESIGN AND METHODS A total of 148 healthy women (aged 53-70 years) underwent a glucose-dependent arginine stimulation test and a 2-h euglycemic-hyperinsulinemic clamp. In the arginine test, arginine (5 g) was injected intravenously under baseline (fasting) conditi...
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OBJECTIVE Recent investigations disclosed an upregulation of retinol-binding protein-4 (RBP4) in the adipose tissue of several insulin-resistant mouse models and increased serum RBP4 concentration in subjects with obesity and type 2 diabetes in association with insulin resistance. There is some experimental evidence that RBP4 also could been linked to insulin secretion. RESEARCH DESIGN AND ME...
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The pattern of endogenous insulin secretion over a 24-h period, which included three mixed meals, was evaluated in 14 normal volunteers and 15 obese subjects. Insulin secretory rates were calculated from plasma C-peptide levels using individually derived C-peptide kinetic parameters and a validated open two-compartment model of peripheral C-peptide kinetics. Insulin secretion rates were consist...
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Adults with GH deficiency are known to exhibit reduced sweating. Whether sweating capacity is impacted in obese subjects with impaired GH secretion have not previously been investigated. The main objective was to investigate sweat secretion rate and the GH-IGF-I axis in obese subjects before and after weight loss. Sixteen severely obese women (BMI, 40.6 ± 1.1 kg/m(2)) were investigated before a...
متن کاملBody Composition in Healthy Obese/Overweight and Normal Weight Subjects Compared to Patients with Metabolic Syndrome
Background: According to previous studies, patient with metabolic syndrome (MetS) are different in terms of body composition from healthy subjects. The purpose of the present study was to determine the body composition of healthy obese/overweight patients and compared them with those having MetS. Methods: A case-control study was conducted on both men and women aged 20 to 55 years, who were sel...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2008
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2007-1212